anti-BTLA Polyclonal Antibody

BTLA

BTLA, CD272

The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain. Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells. Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis

Rabbit

Polyclonal

Rabbit IgG

N/A

Human

Liquid

PBS with 0.09% (W/V) sodium azide. 

Protein A column, followed by peptide affinity purification.

IHC, IF, WB

WB: 1-2 µg/ml; IHC: 2.5 µg/ml; IF: 20 µg/ml

Shelf time: 12 months in temp.: -20 deg.C

gel pack

The antibody solution should be gently mixed before use

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Polyclonals and antibodies

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

anticorps