sRANK Ligand, murine recombinant
Catalog number
4557-1000
Name
sRANK Ligand, murine recombinant
Size
1 mg
Price
4600.00 EUR
Supplier
Details
Synonyms
Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf.
Alternates names
Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf.
Taglines
An osteoclast differentiation and activation factor
Biomolecule/Target
sRANKL
NCBI Gene ID #.
21943
NCBI Gene Symbol
TNF11
Gene Source
Mouse
Accession #
O35235
Recombinant
Yes
Source
E. coli
Purity
≥98%
Activity (Specifications/test method)
N/A
Biological activity
Measured by its ability to induce osteoclast formation in RAW264.7 cells using a concentration of 5-10 ng/ml.
Results
5-10 ng/ml
Molecular Weight
19.4 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized protein
Physical form description
Lyophilized from 5 mM Tris, pH 7.6 + 75 mM NaCl
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1-1.0 mg /ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
Additional source
Recombinants or rec. proteins
Group
recombinants
