anti-Phospho-ASK1 (Ser83) Antibody
Catalog number
A1241-100
Name
anti-Phospho-ASK1 (Ser83) Antibody
Size
Phospho-ASK1 (Ser83) Antibody
Price
360.00 EUR
Supplier
Details
Target of this antibody:
MAP3K5
Alternative names of antibody target:
Mitogen-activated protein kinase kinase kinase 5, Apoptosis signal-regulating kinase 1, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5
Background information:
ASK1 (Apoptosis Signal-regulating Kinase 1) activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activate c-Jun N-terminal Kinase (JNK) and p38 MAP Kinase. ASK1 is activated by TNFR and Fas through the interaction with members of the TRAF Family and the Fas-associated protein Daxx. Overexpression of ASK1 induces apoptosis. However, a catalytically inactive form of ASK1 has been shown to inhibit TNF-α induced apoptosis.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
Clone:
N/A
This antibody reacts with:
Human
Immunogene sequence:
Synthesized peptide derived from human ASK 1 around the phosphorylation site of S83, (20-100aa)
Form of antibody:
Liquid
Formulation of this antibody:
In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Purification method:
Affinity-chromatography using epitope-specific immunogen
This antibody has been succesfully tested for use in following methods:
WB, ELISA, IHC
Recommended usage:
WB 1:500-1:2000; ELISA 1:5000-1:20000; IHC 1:100-1:300
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps
