Recombinant Human Soluble Interleukin-6 (IL-6) Receptor
Catalog number
4598-20
Name
Recombinant Human Soluble Interleukin-6 (IL-6) Receptor
Size
20 µg
Price
359.00 EUR
Supplier
Details
Synonyms
soluble IL-6 receptor alpha, B cell stimulatory factor-2, CD126
Alternates names
soluble IL-6 receptor alpha, B cell stimulatory factor-2, CD126
Taglines
>98% Pure, Active, Human Recombinant Soluble Interleukin-6 (IL-6) Receptor
Biomolecule/Target
Interleukin-6 (IL-6) Receptor
NCBI Gene ID #.
3570
NCBI Gene Symbol
IL6R
Gene Source
Human
Accession #
P08887
Recombinant
Yes
Source
CHO cells
Purity
N/A
Endotoxin Level
N/A
Activity (Specifications/test method)
The ED50 as determined by its ability to intensify the IL-6 induced growth inhibition of murine M1 cells is
Biological activity
The ED50 as determined by its ability to intensify the IL-6 induced growth inhibition of murine M1 cells is
Results
The ED50 as determined by its ability to intensify the IL-6 induced growth inhibition of murine M1 cells is
Molecular Weight
37.6 kDa
Storage Temp.
-20°C
Shipping
Gel Pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized
Physical form description
Lyophilized from 1X PBS, pH 7.2
Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in PBS, pH 7.4. Do not vortex.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Additional source
Recombinants or rec. proteins
Group
recombinants
