Noggin, human recombinant

Catalog number

4675-1000

Size

1 mg

Price

3750.00 EUR

Supplier

Biovision

Order

Details

Synonyms

none

Alternates names

NOG

Taglines

An inhibitor of TGF-β signal transduction

Biomolecule/Target

NCBI Gene ID #.

9241

NCBI Gene Symbol

NOG

Gene Source

Human

Accession #

Q13253

Recombinant

Yes

Source

E. coli

Purity

≥95%

Activity (Specifications/test method)

N/A

Biological activity

Determined by its ability to inhibit 5 ng/ml of BMP-4-induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED₅₀ for the effect is 0.05-0.08 µg/ml of Noggin

Results

0.05-0.08 µg/ml

Molecular Weight

23.1 kDa

Storage Temp.

-20°C

Shipping

Blue ice

Shelf Life

1 year

Concentration

N/A

Appearance

Lyophilized protein

Physical form description

Sterile filtered and lyophilized with no additives

Reconstitution Instructions

Reconstitute in H₂O to a concentration of 0.1 to 1.0 mg/ml. Note: Due to solubility reasons the protein should be kept at low pH. This solution can then be diluted into other aqueous buffers

Handling

Centrifuge the vial prior to opening.

Usage

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants