Caspase-6 Inhibitor Z-VEID-FMK for cell activation

Catalog number
1011-100
Name
Caspase-6 Inhibitor Z-VEID-FMK for cell activation
Size
100 µl
Price
186.00 EUR
Supplier

Details

Description
VEID is the specific recognition sequence for caspase-6/Mch2. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Peptide sequence
Z-Val-E(OMe)-Ile-Asp(OMe)-FMK
CAS number
N/A
Molecular weight
652.9
Category
Caspase Inhibitor
Other name
Z-VEID-FMK, Caspase-6 Inhibitor, VEID-FMK, VEID fluoromethylketone
Molecular formula
C₃₁H₄₅FN₄O₁₀
Physical appearance
Liquid
Supplied with
In DMSO (2 mM)
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>98% by HPLC
Reconstitute instructions
N/A
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
6-12 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.