Cycloheximide for cell activation

Catalog number
1041-1G
Name
Cycloheximide for cell activation
Size
1 g
Price
159.00 EUR
Supplier

Details

Description
A very active antibiotic against many yeasts and fungi. Inhibits protein synthesis in eukaryotes (but not in prokaryotes) by interfering with the translocation step. It inhibits chain initiation as well as chain elongation by acting on the 60S subunit of the eukaryote ribosome, interacting directly with enzyme translocase. Cycloheximide is used as an inhibitor to study cell-free protein biosynthesis in eukaryotes and also used to block ribosome-dependent in vivo polypeptide synthesis. It induces apoptosis in a variety of cells, but can also delay or inhibit apoptosis by other agents.
Peptide sequence
N/A
CAS number
66-81-9
Molecular weight
281.35
Category
Apoptosis Inducer
Other name
3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A
Molecular formula
C₁₅H₂₃NO₄
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>95%
Reconstitute instructions
DMSO or EtOH
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
12 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.