Caspase-1 Substrate YVAD-pNA for cell activation

Ready-to-use colorimetric substrate for caspase-1/ICE and related caspases that recognize the amino acid sequence YVAD. Caspase-1 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate YVAD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for large volume users.

Ac-Tyr-Val-Ala-Asp-pNA

N/A

628.6

Caspase Substrate

Ac-YVAD-pNA, Caspase-1 Substrate, Colorimetric

C₂₉H₃₆N₅O₁₀

Liquid

DMSO (4 mM)

No

No

>98% by HPLC

N/A

-20°C

gel pack

12 months

Protect from light and moisture

cell

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.For cells, cell lines and tissues in culture till half confluency.