Granzyme B Inhibitor Z-AAD-CH2Cl for cell activation

A synthetic peptide that irreversibly inhibits granzyme B activity. The inhibitor is designed as a methyl ester to facilitate cell permeability.

Z-Ala-Ala-Asp(OMe)-CMK

N/A

455.89

Granzyme B

Z-AAD-CMK, Granzyme B Inhibitor(chloromethylketone)

C₂₀H₂₆ClN₃O₇

Liquid

DMSO (10 mM)

No

No

Single spot by TLC

N/A

-20°C

gel pack

12 months

Protect from light and moisture

cell

For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.