Z-IETD-FMK for cell activation
Catalog number
1148-1
Name
Z-IETD-FMK for cell activation
Size
1 mg
Price
306.00 EUR
Supplier
Details
Description
A synthetic peptide that irreversibly inhibits FLICE and related protease/caspase activity and blocks apoptosis. IETD is the specific recognition sequence found in CPP32 proenzyme. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups.)
Peptide sequence
Z-Ile-Glu(OMe)-Thr-Asp(OMe)-FMK
CAS number
N/A
Molecular weight
654.7
Category
Caspase Inhibitor
Other name
Z-IETD-FMK, Z-IETD-fluoromethylketone, Caspase-8 Inhibitor (fluoromethylketone)
Molecular formula
C₃₀H₄₃FN₄O₁₁
Physical appearance
Lyophilized solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
Single spot by TLC
Reconstitute instructions
DMSO (20 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
