Phorbol-12-myristate 13-acetate (PMA) for cell activation
Catalog number
1544-5
Name
Phorbol-12-myristate 13-acetate (PMA) for cell activation
Size
5 mg
Price
186.00 EUR
Supplier
Details
Description
This is the most commonly used phorbol ester. It binds to and activates protein kinase C, causes an extremely wide range of effects in cells and tissues and is a very potent mouse skin tumor promoter. Inhibits apoptosis induced by the Fas antigen, but induced apoptosis in HL-60 promyelocytic leukemia cells
Peptide sequence
N/A
CAS number
16561-29-8
Molecular weight
616.83
Category
Biochemicals
Other name
PMA, 12-O-Tetradecanoylphorbol 13-acetate,TPA, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate
Molecular formula
C₃₆H₅₆O₈
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>99%
Reconstitute instructions
DMSO or EtOH
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
