Tyrphostin AG 490 for cell activation
Catalog number
1570-5
Name
Tyrphostin AG 490 for cell activation
Size
5 mg
Price
159.00 EUR
Supplier
Details
Description
Selectively inhibits EGF receptor auto-phosphorylation (IC₅₀ = 100 µM) and selectively inhibits DNA synthesis and cell growth; induces apoptosis. A JAK2 inhibitor. Blocks growth of leukemia cells in vivo and in vitro.
Peptide sequence
N/A
CAS number
133550-30-8
Molecular weight
294.31
Category
Biochemicals
Other name
2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide; 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide, AG 490
Molecular formula
C₁₇H₁₄N₂O₃
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99%
Reconstitute instructions
DMSO (100 mM) and ETOH (20 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
