Human Recombinant PAI-1

Catalog number

6377-100

Size

100 μg

Price

445.00 EUR

Supplier

Biovision

Order

Details

Synonyms

Human Recombinant PAI-1

Alternates names

Plasminogen activator inhibitor-1, SERPINE1, PAI, PAI1, PLANH1.

Taglines

Activator of plasminogen and fibrinolysis

Biomolecule/Target

NCBI Gene ID #.

5054

NCBI Gene Symbol

SERPINE1

Gene Source

Human

Accession #

P05121

Recombinant

Yes

Source

E. Coli

Purity

N/A

Endotoxin Level

N/A

Activity (Specifications/test method)

N/A

Biological activity

Specific activity, the IC50 value is < 56 nM. Measured by its ability to inhibit uPA cleavage of the substrate Z-GGR-AMC.

Molecular Weight

45 kDa (400 aa, 24-402 aa + NT His-Tag)

Storage Temp.

-20°C

Shipping

gel pack

Shelf Life

1 year

Concentration

1 mg/ml

Appearance

Liquid

Physical form description

1 mg/ml solution in 150 mM Na2HPO4 (pH 6.6) containing 0.5 mM NaCl, 2 mM Glutathione and 0.01% Tween-80.

Reconstitution Instructions

N/A

Handling

Centrifuge the vial prior to opening.

Usage

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene

Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis

Additional source

Recombinants or rec. proteins

Group

recombinants