Cerulenin for cell activation

Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to β-keto-acyl-ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or downstream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes).

N/A

17397-89-6

223.3

Biochemicals

2,3-Epoxy-4-oxo-7,10-dodecadienamide

C₁₂H₁₇NO₃

White to off-white solid

N/A

No

Yes

≥98%

DMSO (20 mg/ml) or EtOH (20 mg/ml)

-20°C

gel pack

24months

Protect from light and air

cell

For cells, cell lines and tissues in culture till half confluency.