Erlotinib, Hydrochloride Salt for cell activation
Catalog number
1588-100
Name
Erlotinib, Hydrochloride Salt for cell activation
Size
100 mg
Price
159.00 EUR
Supplier
Details
Description
Erlotinib is an inhibitor of human Epidermal growth factor receptor (EGFR) tyrosine kinase (IC₅₀ = 2 nM) and decreases EGFR autophosphorylation in tumor cells (IC₅₀ = 20 nM). Studies in cell lines and enzyme assays have both shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl.
Peptide sequence
N/A
CAS number
183319-69-9
Molecular weight
429.9
Category
Biochemicals
Other name
CP-358774, OSI-774
Molecular formula
C₂₂H₂₃N₃O₄.HCl
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
