Erlotinib, Hydrochloride Salt for cell activation
Catalog number
1588-1000
Name
Erlotinib, Hydrochloride Salt for cell activation
Size
1 g
Price
387.00 EUR
Supplier
Details
Description
Erlotinib is an inhibitor of human Epidermal growth factor receptor (EGFR) tyrosine kinase (IC₅₀ = 2 nM) and decreases EGFR autophosphorylation in tumor cells (IC₅₀ = 20 nM). Studies in cell lines and enzyme assays have both shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl.
Peptide sequence
N/A
CAS number
183319-69-9
Molecular weight
429.9
Category
Biochemicals
Other name
CP-358774, OSI-775
Molecular formula
C₂₂H₂₃N₃O₄.HCl
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
