Splitomicin for cell activation
Catalog number
1610-5
Name
Splitomicin for cell activation
Size
5 mg
Price
191.00 EUR
Supplier
Details
Description
Potent inhibitor of yeast NAD⁺-dependent histone deacetylase Sir2p (IC₅₀ = 60 µM). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket.
Peptide sequence
N/A
CAS number
5690-03-9
Molecular weight
198.2
Category
Biochemicals
Other name
1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
Molecular formula
C₁₃H₁₀O₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (100 mg/ml)
Storage condition
+4°C
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
