Panobinostat (LBH589) for cell activation
Catalog number
1612-5
Name
Panobinostat (LBH589) for cell activation
Size
5 mg
Price
420.00 EUR
Supplier
Details
Description
Panobinostat (LBH589) is a highly potent inhibitor of both histone deacetylase 1 (HDAC1) activity and tumour cell proliferation in vitro. The IC₅₀ values of HDAC isozymes HDAC1-IP Ac-H4, HDAC8, MALunselective, B61HDAC1 and B12HDAC6 are 0.23±0.06, 283±29, 75±4, 47±5 and 89±12 nM, respectively. And to A2780 proliferation, IC₅₀ value is 4.6±1.8 nM.
Peptide sequence
N/A
CAS number
404950-80-7
Molecular weight
349.43
Category
Biochemicals
Other name
LBH589, LBN-589, NVP-LBH590
Molecular formula
C₂₁H₂₃N₃O₂
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
