Fingolimod (FTY-720A, FTY720) for cell activation
Catalog number
1618-5
Name
Fingolimod (FTY-720A, FTY720) for cell activation
Size
5 mg
Price
273.00 EUR
Supplier
Details
Description
FTY720 can be phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5). IC₅₀ of (S)- and (R)- FTY720-phosphate on lymphocyte migration toward 10 nM of S1P are 0.137 nM and 10.98 nM respectively. The IC₅₀ values to cell lines MCF-7 is 6.8±0.6 µM.
Peptide sequence
N/A
CAS number
162359-56-0
Molecular weight
343.93
Category
Biochemicals
Other name
FTY-720A, FTY721
Molecular formula
C₁₉H₃₃NO₂.HCl
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (100 mg/ml) of EtOH (100 mg/ml)
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
