Human CellExp™ Activin A, Human Recombinant

Activins are homodimers or heterodimers of the different subunit isoforms, part of the TGF-β super-family. Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells. BioVision’s Activin A is produced in a serum-free, chemically defined media.

N/A

25 kDa, homodimer, nonglycosylated.

Human Cellexp Human Recombinant Activin A

Inhba, Inhibin beta A, FSH releasing protein, FRP

3624

INHBA

Human

P08476

Yes

Human cell expressed

≥95%

SDS-PAGE, N/A

< 1.0 EU per 1 μg of protein

N/A

ED₅₀ is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent inhibition of proliferation of the MPC-11 cell line (mouse plasmocytoma cell line).

0.5 to 5 ng/ml

N/A

N/A

-80°C

gel pack

Lyophilized

Lyophilized from a PBS solution.

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

N/A

Centrifuge the vial prior to opening.

For Research Use Only! Not to be used in humans

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Recombinants or rec. proteins

recombinants