ABT-888 for cell activation
Catalog number
1620-1
Name
ABT-888 for cell activation
Size
1 mg
Price
219.00 EUR
Supplier
Details
Description
Potent inhibitor of PARP-1 and PARP-2 (potency ≤5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radio-potentiation. Does not show inherent cytotoxicity and shows no single agent activity in tumor models.
Peptide sequence
N/A
CAS number
912445-05-7
Molecular weight
317.21
Category
Biochemicals
Other name
2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide . dihydrochloride
Molecular formula
C₁₃H₁₆N₄O.2HCl
Physical appearance
Coloreless to white crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO and H₂O
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
