Human CellExp™ BMP-7, Human Recombinant

Catalog number

6446-10

Size

10 μg

Price

382.00 EUR

Supplier

Biovision

Order

Details

Background

BMP7 belongs to the transforming growth factor-beta (TGFβ) superfamily. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Based on its expression early in embryogenesis, BMP-7 has a proposed role in early development. In addition, the fact that BMP-7 is closely related to BMP5 has led to speculation of possible bone inductive activity.

Concentration

N/A

Molecular weight

30 to 38 kDa, homodimer, glycosylated.

Synonym

Human Cellexp Human Recombinant BMP-7

Other name

Osteogenic Protein 1, BMP-7

NCBI gene number

655

NCBI gene

BMP7

Gene source

Human

NCBI number

P18075

Recombinant

Yes

Source

Human 293 cell expressed

Purification

≥95%

Tested applications

SDS-PAGE, N/A

Level of endotoxin

< 1.0 EU per 1 μg of protein

Tested activity

N/A

Biological activity

ED₅₀ is typically 50 to 250 ng/mL. The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).

Reesults

50 to 250 ng/ml

Binding ability

N/A

Unit

N/A

Storage condition

-80°C

Shipping under

gel pack

Physical appearance

Lyophilized

Physical properties

Lyophilized from a solution of 50 mM sodium acetate, pH 4.5, with 50 mM NaCl.

How to reconstitute

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Aa sequence

N/A

Before use

Centrifuge the vial prior to opening.

Notes

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants