PD-0325901 for cell activation
Catalog number
1643-2
Name
PD-0325901 for cell activation
Size
2 mg
Price
191.00 EUR
Supplier
Details
Description
A selective and ATP non-competitive MEK inhibitor that suppresses the phosphorylation of ERK in murine colon 26 tumors (IC₅₀ = 0.33 nM). In combination with the GSK-3 inhibitor CHIR99021, prevents cell differentiation and sustains self-renewal of embryonic stem (ES) cells.
Peptide sequence
N/A
CAS number
391210-10-9
Molecular weight
482.2
Category
Biochemicals
Other name
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2[(2-fluoro-4-iodophenyl)amino]-benzamide
Molecular formula
C₁₆H₁₄F₃IN₂O₄
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO (20 mg/ml) of EtOH (20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
