Cambinol for cell activation
Catalog number
1653-10
Name
Cambinol for cell activation
Size
10 mg
Price
251.00 EUR
Supplier
Details
Description
An inhibitor of NAD-dependent deacetylase activity of human SIRT1 (IC₅₀ = 56 µM) and SIRT2(IC₅₀ = 59 µM). Acts as an antitumor agent. Treatment of BCL6-expressing Burkitt lymphoma cells with Cambinol induces apoptosis accompanied by hyperacetylation of BCL6 and p53.
Peptide sequence
N/A
CAS number
14513-15-6
Molecular weight
360.43
Category
Biochemicals
Other name
5-[(2-hydroxy-5,8-dihydronaphthalen-1-yl)methyl]-6-phenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; NSC-112546
Molecular formula
C₂₁H₁₆N₂O₂S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO (10 mg/ml)
Storage condition
+4°C
Shipping condition
RT
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
