PAC-1 for cell activation
Catalog number
1654-10
Name
PAC-1 for cell activation
Size
10 mg
Price
159.00 EUR
Supplier
Details
Description
Procaspase-activating compound 1 (PAC-1) directly activates procaspase-3 to caspase-3, a transformation that allows induction of apoptosis even in cells that have defective apoptotic machinery. In cancer cells, PAC-1 had an IC₅₀ value of 3 nM for induction of cell death, whereas in cells from adjacent normal tissue had IC₅₀ values of 3.2-8.5 µM.
Peptide sequence
N/A
CAS number
315183-21-2
Molecular weight
392.49
Category
Biochemicals
Other name
2-[[2-Hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide 4-(phenylmethyl)-1-piperazineacetic acid
Molecular formula
C₂₃H₂₈N₄O₂
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO
Storage condition
+4°C
Shipping condition
RT
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
