PP242 for cell activation

Catalog number
1658-1
Name
PP242 for cell activation
Size
1 mg
Price
191.00 EUR
Supplier

Details

Description
A potent and selective in vitro mTOR inhibitor that targets the ATP domain of mTOR (IC₅₀ = 8 nM). Inhibits other PI 3-Kinases only at much higher concentrations. Recently it has been shown that PP242 is a more effective mTORC1 inhibitor than Rapamycin (Cat. No. 1568-5 & 1568-50).
Peptide sequence
N/A
CAS number
1092351-67-1
Molecular weight
308.34
Category
Biochemicals
Other name
2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol
Molecular formula
C₁₆H₁₆N₆O
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>50 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.