U0126 for cell activation

Catalog number
1668-5
Name
U0126 for cell activation
Size
5 mg
Price
191.00 EUR
Supplier

Details

Description
Potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (IC₅₀ values of 0.07 and 0.06 µM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4.
Peptide sequence
N/A
CAS number
109511-58-2
Molecular weight
380.48
Category
Biochemicals
Other name
1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene
Molecular formula
C₁₈H₁₆N₆S₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.