SB-431542 for cell activation
Catalog number
1674-5
Name
SB-431542 for cell activation
Size
5 mg
Price
436.00 EUR
Supplier
Details
Description
A potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC₅₀ = 94 nM). It inhibits ALK4 only at higher concentrations (IC₅₀ = 140 nM). Suppresses renewal in embryonic and induced pluripotent stem (iPS) cells and promotes their differentiation through its effect on Smad signaling pathway.
Peptide sequence
N/A
CAS number
301836-41-9
Molecular weight
384.39
Category
Biochemicals
Other name
4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Molecular formula
C₂₂H₁₈N₄O₃
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (20 mg/ml) or EtOH (2 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
