PD 173074 for cell activation
Catalog number
1675-1
Name
PD 173074 for cell activation
Size
1 mg
Price
137.00 EUR
Supplier
Details
Description
A potent and selective FGFR1 tyrosine kinase inhibitor (IC₅₀ = 21.5 nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem cells with PD173074 decreases dramatically their clonogenicity and differentiation potential.
Peptide sequence
N/A
CAS number
219580-11-7
Molecular weight
523.67
Category
Biochemicals
Other name
N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea
Molecular formula
C₂₈H₄₁N₇O₃
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
