Thiazovivin for cell activation

Catalog number
1681-1
Name
Thiazovivin for cell activation
Size
1 mg
Price
191.00 EUR
Supplier

Details

Description
Cell-permeable. Helps in promoting human embryonic stem cell (hESC) survival by > 30-fold. Thiazovivin enhances the efficiency of fibroblast reprogramming to generate induced pluripotent stem cells (iPSCs) when used in combination with SB-431542 (Cat. No. 1674) and PD 0325901 (Cat. No.1643).Acts as a Rho-associated Kinase (ROCK) inhibitor. Tzv (2 µM) inhibits ROCK activity and protect hESCs at a similar level as Y-27632 (10 µM) (Cat. No. 1596), a well-known, selective ROCK inhibitor.
Peptide sequence
N/A
CAS number
1226056-71-8
Molecular weight
311.36
Category
Biochemicals
Other name
N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide; Tzv
Molecular formula
C₁₅H₁₃N₅OS
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (100 mM)
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.