Human CellExp™ TGF-beta 3, Human Recombinant

Catalog number

6481-10

Size

10 µg

Price

621.00 EUR

Supplier

Biovision

Order

Details

Background

Transforming growth factor betas (TGFβ) mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-beta 3 influences pathogenesis and pulmonary development.

Concentration

N/A

Molecular weight

25 kDa, homodimer, nonglycosylated

Synonym

Human Cellexp Human Recombinant TGF-beta 3

Other name

Transforming Growth Factor-beta3, TGFB3, ARVD, FLJ16571, TGF-beta 3.

NCBI gene number

7043

NCBI gene

TGFB3

Gene source

Human

NCBI number

P10600

Recombinant

Yes

Source

Human 293 cell expressed

Purification

> 95%

Tested applications

SDS-PAGE, N/A

Level of endotoxin

< 1.0 EU per 1 μg of protein

Tested activity

N/A

Biological activity

ED₅₀ is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).

Reesults

0.1 to 0.5 ng/ml

Binding ability

N/A

Unit

N/A

Storage condition

-80°C

Shipping under

gel pack

Physical appearance

Lyophilized

Physical properties

Lyophilized from 50 mM sodium acetate, pH 4.5 and 350 mM NaCl.

How to reconstitute

Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin.

Aa sequence

N/A

Before use

Centrifuge the vial prior to opening.

Notes

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants