Human CellExp™ TPO, Human Recombinant

Catalog number

6483-50

Size

50 µg

Price

1980.00 EUR

Supplier

Biovision

Order

Details

Background

TPO (Thrombopoietin, also known as Mpl-ligand, MGDF), a glycoprotein hormone produced mainly by the liver and the kidney, stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets.

Concentration

N/A

Molecular weight

80 to 85 kDa, monomer, glycosylated

Synonym

Human Cellexp Human Recombinant TPO

Other name

Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.

NCBI gene number

7066

NCBI gene

THPO

Gene source

Human

NCBI number

P40225

Recombinant

Yes

Source

Human 293 cell expressed

Purification

> 95%

Tested applications

SDS-PAGE, N/A

Level of endotoxin

< 1.0 EU per 1 μg of protein

Tested activity

N/A

Biological activity

ED₅₀ is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of human M07e cells

Reesults

0.5 to 5 ng/ml

Binding ability

N/A

Unit

N/A

Storage condition

-80°C

Shipping under

gel pack

Physical appearance

Lyophilized

Physical properties

Lyophilized in PBS.

How to reconstitute

Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Aa sequence

N/A

Before use

Centrifuge the vial prior to opening.

Notes

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants