Fludarabine Phosphate for cell activation
Catalog number
1763-10
Name
Fludarabine Phosphate for cell activation
Size
10 mg
Price
137.00 EUR
Supplier
Details
Description
A chemotherapy drug used in the treatment of hematological malignancies. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase-⍺, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.
Peptide sequence
N/A
CAS number
75607-67-9
Molecular weight
365.21
Category
Biochemicals
Other name
[(2R,3R,4S,5R)-5-(6-amino-2-fluoro-purin-9-yl)- 3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid; Fludara
Molecular formula
C₁₀H₁₃FN₅O₇P
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥98%
Reconstitute instructions
DMSO or H₂O (5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
