SB 216763 for cell activation
Catalog number
1769-5
Name
SB 216763 for cell activation
Size
5 mg
Price
387.00 EUR
Supplier
Details
Description
A potent, cell-permeable and ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3) (Ki= 9 nM for GSK-3α). Has little activity against 24 other protein kinases (IC₅₀ > 10 μM). Stimulates glycogen synthesis, gene transcription and is neuroprotective.
Peptide sequence
N/A
CAS number
280744-09-4
Molecular weight
371.22
Category
Biochemicals
Other name
3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Molecular formula
C₁₉H₁₂Cl₂N₂O₂
Physical appearance
Orange solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (50 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
