Fasudil, Monohydrochloride for cell activation
Catalog number
1787-50
Name
Fasudil, Monohydrochloride for cell activation
Size
50 mg
Price
425.00 EUR
Supplier
Details
Description
A cell-permeable Ca²⁺ antagonist and vasodilator. Inhibits protein kinase A (Ki = 1.6 µM), protein kinase G (Ki = 1.6 µM), myosin light chain kinase (Ki = 36 µM) and Rho kinase (ROCK; IC₅₀ = 10.7 µM. Fasudil also mobilizes adult neural stem cells in vivo.
Peptide sequence
N/A
CAS number
105628-07-7
Molecular weight
327.83
Category
Biochemicals
Other name
1-(5-Isoquinolinesulfonyl)homopiperazine, Monohydrochloride Salt; HA-1077, Monohydrochloride; AT-878
Molecular formula
C₁₄H₁₇N₃O₂S•HCl
Physical appearance
White to off-white solid
Supplied with
Water (175 mg/ml) or DMSO (10 mg/ml)
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99% by HPLC
Reconstitute instructions
Water (175 mg/ml) or DMSO (10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
DMSO (100 mM) or EtOH (10 mM)
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
