Marimastat for cell activation
Catalog number
1790-1
Name
Marimastat for cell activation
Size
1 mg
Price
170.00 EUR
Supplier
Details
Description
A broad spectrum matrix metalloprotease (MMP) inhibitor with IC₅₀ values of 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively. It covalently binds to the zinc(II) ion in the active site of MMPs, thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
Peptide sequence
N/A
CAS number
154039-60-8
Molecular weight
331.41
Category
Biochemicals
Other name
(2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide; BB-2516; TA-2516; Marimistat
Molecular formula
C₁₅H₂₉N₃O₅
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (100 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
