Bay 61-3606 Hydrochloride for cell activation
Catalog number
1796-1
Name
Bay 61-3606 Hydrochloride for cell activation
Size
1 mg
Price
159.00 EUR
Supplier
Details
Description
Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC₅₀ = 10 nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7 µM. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models.
Peptide sequence
N/A
CAS number
732983-37-8
Molecular weight
426.86
Category
Biochemicals
Other name
2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide, HCl
Molecular formula
C₂₀H₁₈N₆O₃.HCl
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
H₂O (30 mg/ml) DMSO (2 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
