Niclosamide for cell activation
Catalog number
1826-500
Name
Niclosamide for cell activation
Size
500 mg
Price
349.00 EUR
Supplier
Details
Description
A STAT3 signaling pathway inhibitor. Niclosamide potently inhibits the activation and transcriptional function of STAT3 and induces cell growth inhibition, apoptosis, and cell cycle arrest of cancer cells with constitutively active STAT3. Also reversibly inhibits mTORC1 signaling and stimulates autophagy in vitro; displays antineoplastic effects in acute myelogenous leukemia (AML) stem cells.
Peptide sequence
N/A
CAS number
50-65-7
Molecular weight
327.12
Category
Biochemicals
Other name
5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
Molecular formula
C₁₃H₈Cl₂N₂O₄
Physical appearance
Off-white to pale yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (10 mM) or Ethanol (25 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
