8-Br-cAMP for cell activation
Catalog number
1837-5
Name
8-Br-cAMP for cell activation
Size
5 mg
Price
121.00 EUR
Supplier
Details
Description
A cell-permeable cAMP analog that is more resistant to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells. Also recently shown to improve the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells 2-fold.
Peptide sequence
N/A
CAS number
76939-46-3
Molecular weight
430.08
Category
Biochemicals
Other name
8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic 8- bromoadenosine- 3', 5'- monophosphate; 8- bromoadenosine- 3', 5'-Monophosphate
Molecular formula
C₁₀H₁₀BrN₅O₆P. Na
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
H₂O (~100 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from moisture and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
