8-Br-cGMP for cell activation
Catalog number
1838-25
Name
8-Br-cGMP for cell activation
Size
25 mg
Price
273.00 EUR
Supplier
Details
Description
A cell-permeable cGMP analog having greater resistance to hydrolysis by phosphodiesterases than cGMP. Activates cGMP-dependent protein kinase (PKG), slows or inhibits the intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine. It inhibits thrombin stimulated arachidonic acid release in human platelets.
Peptide sequence
N/A
CAS number
51116-01-9
Molecular weight
446.08
Category
Biochemicals
Other name
8- Bromoguanosine- 3', 5'- cyclic monophosphate, cyclic 8- bromoguanosine- 3', 5'- monophosphate, 8- bromoguanosine- 3', 5'-monophosphate
Molecular formula
C₁₀H₁₀BrN₅O₇P. Na
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by TLC
Reconstitute instructions
H₂O (~25 mg/ml) or aqueous buffers
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from moisture and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
