Persephin, human recombinant

Catalog number

7185-50

Size

50 μg

Price

725.00 EUR

Supplier

Biovision

Order

Details

Synonyms

PSP, PSPN

Alternates names

PSP, PSPN

Taglines

Promotes the survival of ventral midbrain dompaminergic neurons and motor neurons

Biomolecule/Target

Persephin

NCBI Gene ID #.

5623

NCBI Gene Symbol

PSPN

Gene Source

Human

Accession #

O60542

Recombinant

Yes

Source

E. Coli

Purity

N/A

Endotoxin Level

< 0.1 ng/μg of protein (

Activity (Specifications/test method)

Human Persephin induces RET phosphorylation using a concentration range of 0.1-1.0 ng/ml. Human Persephin binds to mammalian GFRα4 with the Kd of 100pM. Other members of the GDNF family (Artemin, GDNF and Neurturin) do not bind to mammalian GFRα4.

Biological activity

Results

N/A

Molecular Weight

10.4 kDa

Storage Temp.

-20°C

Shipping

Gel Pack

Shelf Life

1 year

Concentration

N/A

Appearance

Lyophilized powder

Physical form description

Sterile filtered through a 0.2 micron filter. Lyophilized from 0.3 x PBS, pH 7.2

Reconstitution Instructions

Centrifuge the vial prior to opening. Reconstitute in 5 mM Sodium Phosphate, pH 7.5 to a concentration of ≤ 0.5 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Handling

Centrifuge the vial prior to opening.

Usage

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants