SMER28 for cell activation
Catalog number
1856-5
Name
SMER28 for cell activation
Size
5 mg
Price
181.00 EUR
Supplier
Details
Description
Cell permeable. Acts as a positive regulator of autophagy, acting via mTOR-independent mechanism. SMER28 increases autophagosome synthesis and enhances the clearance of model autophagy substrates such as A53T a-synuclein and mutant huntingtin fragments. It is also protective in Drosophila model of Huntington’s Disease (HD).
Peptide sequence
N/A
CAS number
307538-42-7
Molecular weight
264.12
Category
Biochemicals
Other name
Small-Molecule Enhancer of Rapamycin-28;6-Bromo-4-allylaminoquinazoline
Molecular formula
C₁₁H₁₀BrN₃
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (~8 mg/ml) or EtOH (~ 2 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
