Necrostatin-1 for cell activation
Catalog number
1864-5
Name
Necrostatin-1 for cell activation
Size
5 mg
Price
121.00 EUR
Supplier
Details
Description
Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC₅₀ = 180 nM).
Peptide sequence
N/A
CAS number
4311-88-0
Molecular weight
259.33
Category
Biochemicals
Other name
5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone; Methylthiohydantoin-DL-tryptophan; Nec-1
Molecular formula
C₁₃H₁₃N₃OS
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (~25 mg/ml) or EtOH (~ 6 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
