Necrostatin-5 for cell activation
Catalog number
1865-5
Name
Necrostatin-5 for cell activation
Size
5 mg
Price
126.00 EUR
Supplier
Details
Description
Inhibits non-apoptotic cell death pathway by inhibition of the death domain receptor-associated adaptor kinase RIP1. Three distinct mechanisms appear to be involved in necroptosis, the alternative active cell death pathway: T-loop dependent inhibition by necrostatin-1; partially T-loop independent inhibition by necrostatin-3 and indirect inhibition of RIP1 by necrostatin-5.
Peptide sequence
N/A
CAS number
337349-54-9
Molecular weight
383.49
Category
Biochemicals
Other name
3-p-Methoxyphenyl-5,6-tetramethylenothieno[2,3-d]pyrimidin-4-one-2-mercaptoethylcyanide; Nec-5
Molecular formula
C₁₉H₁₇N₃O₂S₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by NMR
Reconstitute instructions
DMSO (~10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
