BAY 11-7082 for cell activation
Catalog number
1867-50
Name
BAY 11-7082 for cell activation
Size
50 mg
Price
567.00 EUR
Supplier
Details
Description
Potential anti-inflammatory agent. Selectively and irreversibly inhibits NF-κB activation by blocking TNF-α-induced phosphorylation of IκB-α without affecting constitutive IκB-α phosphorylation. Inhibits the TNF-α-induced surface expression of adhesion molecules ICAM-1, VCAM-1, and E-selectin in human endothelial cells with IC₅₀ values of 5-10 µM.
Peptide sequence
N/A
CAS number
19542-67-7
Molecular weight
207.25
Category
Biochemicals
Other name
(E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile
Molecular formula
C₁₀H₉NO₂S
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO or EtOH
Storage condition
+4°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
