SC66 for cell activation

Catalog number
1870-50
Name
SC66 for cell activation
Size
50 mg
Price
387.00 EUR
Supplier

Details

Description
Cell-permeable. An allosteic Akt inhibitor that directly facilitates Akt ubiquitination in vitro and in vivo. SC66 displays a dual inhibitory activity that directly interferes with the pleckstrin homology (PH) domain binding to PIP₃ and facilitates Akt ubiquitination. Due to its dual inhibitory activity, SC66 displays a more effective growth suppression of transformed cells that contain a high level of Akt signaling, compared with other inhibitors of PIP₃/Akt pathway.
Peptide sequence
N/A
CAS number
871361-88-5
Molecular weight
276.33
Category
Biochemicals
Other name
(2E, 6E)-2, 6-Bis(pyridine-4ylmethylene)cyclohexanone
Molecular formula
C₁₈H₁₆N₂O
Physical appearance
Yellow crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.