RepSox for cell activation
Catalog number
1894-25
Name
RepSox for cell activation
Size
25 mg
Price
387.00 EUR
Supplier
Details
Description
Cell-permeable. A TGF-β type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC₅₀ = 4 nM). Can replace one of the four reprogramming factors Sox-2. RepSox has been successfully used in the direct reprogramming of mouse fibroblasts through induction of Nanog transcription.
Peptide sequence
N/A
CAS number
446859-33-2
Molecular weight
287.32
Category
Biochemicals
Other name
2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E-616452
Molecular formula
C₁₇H₁₃N₅
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
