MIF-Antagonist, ISO-1 for cell activation
Catalog number
1895-5
Name
MIF-Antagonist, ISO-1 for cell activation
Size
5 mg
Price
159.00 EUR
Supplier
Details
Description
Cell-permeable. A macrophage migration inhibitory factor (MIF) antagonist. ISO-1 inhibits MIF pro-inflammatory activities by targeting MIF tautomerase activity. Also inhibits tumor necrosis factor (TNF) release from macrophages isolated from LPS- treated wild type mice but has no effect on cytokine release from MIF deficient macrophages.
Peptide sequence
N/A
CAS number
478336-92-4
Molecular weight
235.24
Category
Biochemicals
Other name
(S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl ester
Molecular formula
C₁₂H₁₃NO₄
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~25 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
The antagonist receptor ligand binding will be in contrast with agonist activity. Biovision produces more antagonist and receptor related products as 1.For cells, cell lines and tissues in culture till half confluency.
