SR1001 for cell activation
Catalog number
1902-5
Name
SR1001 for cell activation
Size
5 mg
Price
159.00 EUR
Supplier
Details
Description
Cell-permeable. A high affinity synthetic ligand specific to both retinoic acid-related orphan receptors ɑ (RORɑ) and γt (RORγt). SR1001 inhibits interleukin-17 (TH17) cell differentiation and function as well as suppressing the clinical severity of autoimmune disease in mice.
Peptide sequence
N/A
CAS number
N/A
Molecular weight
477.4
Category
Biochemicals
Other name
N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulphamoyl)-4-methylthiazol-2-yl)acetamide
Molecular formula
C₁₅H₁₃F₆N₃O₄S₂
Physical appearance
Cream solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC and NMR
Reconstitute instructions
DMSO (10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.