Kenpaullone for cell activation
Catalog number
1904-1
Name
Kenpaullone for cell activation
Size
1 mg
Price
137.00 EUR
Supplier
Details
Description
Cell-permeable. A potent inhibitor of CDK1/cyclin B (IC₅₀ = 400 nM), CDK2/cyclin A (IC₅₀ = 680nM) , CDK5 (IC₅₀ = 850nM) and with much less effect other kinases. In addition, it has been found to be a useful GSK-3β inhibitor (IC₅₀ = 23nM). More recently, kenpaullone has been shown to increase neurogenesis of human neural progenitor cells through stimulation of Wnt/β-catenin signaling pathway.
Peptide sequence
N/A
CAS number
142273-20-9
Molecular weight
327.18
Category
Biochemicals
Other name
9-Bromo-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one
Molecular formula
C₁₆H₁₁BrN₂O
Physical appearance
Tan solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (>25 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
